MYT1L antibody (C-Term)

Catalog No. ABIN6991773

The Rabbit Polyclonal anti-MYT1L antibody (ABIN6991773) specifically detects MYT1L in WB, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for MYT1L antibody (C-Term) (ABIN6991773)

Target: MYT1L (Myelin Transcription Factor 1-Like (MYT1L))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYT1L antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-MYT1L Antibody

Binding Specificity: C-Term

Specificity: At least three isoforms are known to exist. This antibody will only recognize the two longest isoforms.

Purification: MYT1L Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal MYT1L antibody was raised against an 18 amino acid peptide near the carboxy terminus of human MYT1L. The immunogen is located within the last 50 amino acids of MYT1L.

Isotype: IgG

Application Details

Application Notes: MYT1L antibody can be used for detection of MYT1L by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: MYT1L Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: MYT1L antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for MYT1L

Target: MYT1L (Myelin Transcription Factor 1-Like (MYT1L))

Alternative Name: MYT1L

Background: MYT1L Antibody: The myelin transcription factor 1 family, to which the myelin transcription factor 1-like protein (MYT1L) belongs, is expressed primarily in the developing central nervous system and recruits histone deacetylase (HDAC) to regulate neural transcription. Both MYT1L and the related protein MYT1 interact with SIN3B, a protein that mediates transcriptional repression by binding to HDACs, suggesting that the MYT1 family favor the silencing of genes during neural development. Recent studies suggest that polymorphisms of MYT1L may be associated with schizophrenia.

Molecular Weight: 130 kDa

Gene ID: 23040

NCBI Accession: NP_055840

UniProt: Q9UL68