KRT20 antibody (AA 196-323)

Catalog No. ABIN7871725

The Mouse Monoclonal anti-KRT20 antibody (Clone KRT20-1993) (ABIN7871725) specifically detects KRT20 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for KRT20 antibody (AA 196-323) (ABIN7871725)

Target: KRT20 (Keratin 20 (KRT20))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KRT20 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: KRT20-1993

Product Details anti-KRT20 Antibody

Binding Specificity: AA 196-323

Purpose: CK20 Antibody / Cytokeratin 20 / KRT20 (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: A portion of amino acids 196-323 from the human protein was used as the immunogen for this CK20 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the CK20 antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the CK20 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for KRT20

Target: KRT20 (Keratin 20 (KRT20))

Alternative Name: CK20

Background: This mAb recognizes an intermediate filament protein of 46 kDa, identified as Cytokeratin 20 (KRT20, CK20). KRT is abundantly expressed in goblet cells and enterocytes of the gastrointestinal tract. It is a useful marker of pancreatic and colorectal cancer. KRT20 is expressed under normal, hyperplastic and neoplastic conditions. It has been detected in adenocarcinomas of the colon, stomach and biliary tract. Breast carcinomas are generally non-reactive.

UniProt: P35900