EIF1 antibody (AA 2-106)

Catalog No. ABIN7871762

This Rabbit Polyclonal antibody specifically detects EIF1 in WB, ELISA, IF, IHC (p) and FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for EIF1 antibody (AA 2-106) (ABIN7871762)

Target: EIF1 (Eukaryotic Translation Initiation Factor 1 (EIF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-EIF1 Antibody

Binding Specificity: AA 2-106

Purpose: Eukaryotic translation initiation factor 1 Antibody / EIF1

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids S2-D106) was used as the immunogen for the Eukaryotic translation initiation factor 1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Eukaryotic translation initiation factor 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Eukaryotic translation initiation factor 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for EIF1

Target: EIF1 (Eukaryotic Translation Initiation Factor 1 (EIF1))

Alternative Name: Eukaryotic translation initiation factor 1

Background: Eukaryotic translation initiation factor 1 (eIF1) is a protein that in humans is encoded by the EIF1 gene. It is related to yeast SUI1. In mammalian cells, translation is controlled at the level of polypeptide chain initiation by initiation factors. Eukaryotic translation initiation factor 1 (eIF1) is crucial for the scanning process in vitro. During the scanning process, eIF1 is a component of a complex involved in recognition of the initiator codon. Translation is also initiated by the role of eIF1 in regulating the activity of ribosomal subunits 43S, 48S and 40S. eIF1 enables 43S ribosomal complexes to discern between cognate and near-cognate initiation codons, sensing the nucleotide content of initiation codons. It is also a promotor, along with eukar-yotic translation initiation factor 1A (eIF1A), for assembly of 48S ribosomal complexes at the initiation codon of a conventional capped mRNA. In addition, eIF1 and eIF1A, together with eukaryotic translation initiation factor 5 (eIF5), function in the formation of stable 40S ribosomal preinitiation complexes.

UniProt: P41567