Recombinant TCL1A antibody (AA 2-109)

Catalog No. ABIN7871764

The Rabbit Monoclonal anti-TCL1A antibody (Clone TCL1-2747R) (ABIN7871764) specifically detects TCL1A in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant TCL1A antibody (AA 2-109) (ABIN7871764)

Target: TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This TCL1A antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: TCL1-2747R

Product Details anti-TCL1A Antibody

Binding Specificity: AA 2-109

Purpose: Recombinant TCL1 Antibody

Purification: Protein A affinity chromatography

Immunogen: A portion of amino acids 2-109 from the human protein was used as the immunogen for the recombinant TCL1 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the recombinant TCL1 antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant TCL1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for TCL1A

Target: TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Alternative Name: TCL1

Background: T-cell leukemia/Lymphoma Protein 1A (TCL-1A), also known as p14TCL1 is a product of the TCL1 gene that is involved in T-cell prolymphocytic leukemia (TPLL). T-PLL is a rare form of mature T-cell leukemia, which is consistently associated with chromosomal rearrangements characterized by the juxtaposition of the TCRA locus on chromosome 14q11 and the TCL1A gene on 14q32.13. TCL1 is overexpressed in Burkitt lymphoma, the majority of AIDS-related non-Hodgkin lymphoma-designated immunoblastic plasmacytoid lymphoma, lymphoblastic lymphoma, chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, diffuse large B-cell lymphoma, and primary cutaneous B-cell lymphoma.

UniProt: P56279

Pathways: Stem Cell Maintenance