TCL1A antibody (AA 2-109)

Catalog No. ABIN7871766

The Mouse Monoclonal anti-TCL1A antibody is suitable to detect TCL1A in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for TCL1A antibody (AA 2-109) (ABIN7871766)

Target: TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TCL1A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: TCL1-2079

Product Details anti-TCL1A Antibody

Binding Specificity: AA 2-109

Purpose: TCL1 Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: A portion of amino acids 2-109 from the human protein was used as the immunogen for the TCL1 antibody.

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal dilution of the TCL1 antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the TCL1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for TCL1A

Target: TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Alternative Name: TCL1

Background: T-cell leukemia/Lymphoma Protein 1A (TCL-1A), also known as p14TCL1 is a product of the TCL1 gene that is involved in T-cell prolymphocytic leukemia (TPLL). T-PLL is a rare form of mature T-cell leukemia, which is consistently associated with chromosomal rearrangements characterized by the juxtaposition of the TCRA locus on chromosome 14q11 and the TCL1A gene on 14q32.13. TCL1 is overexpressed in Burkitt lymphoma, the majority of AIDS-related non-Hodgkin lymphoma-designated immunoblastic plasmacytoid lymphoma, lymphoblastic lymphoma, chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, diffuse large B-cell lymphoma, and primary cutaneous B-cell lymphoma.

UniProt: P56279

Pathways: Stem Cell Maintenance