GCHFR antibody (AA 2-84)

Catalog No. ABIN7871826

The Rabbit Polyclonal anti-GCHFR antibody is suitable to detect GCHFR in samples from Human, Rat and Mouse. It has been validated for ELISA, WB, IF, IHC (p) and FACS.

Quick Overview for GCHFR antibody (AA 2-84) (ABIN7871826)

Target: GCHFR (GTP Cyclohydrolase I Feedback Regulator (GCHFR))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCHFR antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-GCHFR Antibody

Binding Specificity: AA 2-84

Purpose: GCHFR Antibody

Purification: Affinity purified

Immunogen: A human recombinant partial protein (amino acids P2-E84) was used as the immunogen for the GCHFR antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the GCHFR antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the GCHFR antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for GCHFR

Target: GCHFR (GTP Cyclohydrolase I Feedback Regulator (GCHFR))

Alternative Name: GCHFR

Background: GTP cyclohydrolase 1 feedback regulatory protein is an enzyme that in humans is encoded by the GCHFR gene. GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide.

UniProt: P30047