TARBP2 antibody (AA 20-366)

Catalog No. ABIN7871866

The Rabbit Polyclonal anti-TARBP2 antibody (ABIN7871866) specifically detects TARBP2 in WB, IF, ELISA, FACS and IHC (p). The antibody is reactive with Human and Rat samples.

Quick Overview for TARBP2 antibody (AA 20-366) (ABIN7871866)

Target: TARBP2 (TAR (HIV-1) RNA Binding Protein 2 (TARBP2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TARBP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TARBP2 Antibody

Binding Specificity: AA 20-366

Purpose: TARBP2 Antibody / TRBP

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids E20-K366) was used as the immunogen for the TARBP2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the TARBP2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the TARBP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for TARBP2

Target: TARBP2 (TAR (HIV-1) RNA Binding Protein 2 (TARBP2))

Alternative Name: TARBP2

Background: RISC-loading complex subunit TARBP2, also called TRBP and Trans-activation-responsive RNA-binding protein, is a protein that in humans is encoded by the TARBP2 gene. HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene.

UniProt: Q15633

Pathways: Regulatory RNA Pathways, Ribonucleoprotein Complex Subunit Organization