ENDOU antibody (AA 20-386)

Catalog No. ABIN7871869

The Rabbit Polyclonal anti-ENDOU antibody (ABIN7871869) specifically detects ENDOU in WB, ELISA, FACS, IF and IHC (p). The antibody is reactive with Human samples.

Quick Overview for ENDOU antibody (AA 20-386) (ABIN7871869)

Target: ENDOU (Endonuclease, PolyU-Specific (ENDOU))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENDOU antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ENDOU Antibody

Binding Specificity: AA 20-386

Purpose: Uridylate-specific endoribonuclease Antibody / PP11 / ENDOU

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids K20-T386) was used as the immunogen for the Uridylate-specific endoribonuclease antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Uridylate-specific endoribonuclease antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Uridylate-specific endoribonuclease antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ENDOU

Target: ENDOU (Endonuclease, PolyU-Specific (ENDOU))

Alternative Name: Uridylate-specific endoribonuclease

Background: Endonuclease, poly(U) specific is a protein that in humans is encoded by the ENDOU gene. This gene encodes a protein with endoribonuclease activity that binds polyuridine-enriched single-stranded RNA. This gene was initially characterized based on its high expression in placenta but was mischaracterized as a serine protease. In mouse, this gene promotes tolerance to self-antigens by regulating B cell activation-induced cell death (AICD). The protein may be useful as a tumor marker. Multiple alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.

UniProt: P21128