PDIA6 antibody (AA 20-440)

Catalog No. ABIN7871873

This Mouse Monoclonal antibody specifically detects PDIA6 in WB, IF, FACS and IHC (p). It exhibits reactivity toward Human and Monkey.

Quick Overview for PDIA6 antibody (AA 20-440) (ABIN7871873)

Target: PDIA6 (Protein Disulfide Isomerase Family A, Member 6 (PDIA6))

Reactivity: Human, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This PDIA6 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3H5E7

Product Details anti-PDIA6 Antibody

Binding Specificity: AA 20-440

Purpose: PDIA6 Antibody / ERp5

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids L20-L440) was used as the immunogen for the PDIA6 antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the PDIA6 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PDIA6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PDIA6

Target: PDIA6 (Protein Disulfide Isomerase Family A, Member 6 (PDIA6))

Alternative Name: PDIA6

Background: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. This protein inhibits the aggregation of misfolded proteins and exhibits both isomerase and chaperone activity. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: Q15084

Pathways: ER-Nucleus Signaling, Cell RedoxHomeostasis