PDIA6 antibody (AA 20-440)

Catalog No. ABIN7871874

The Rabbit Polyclonal anti-PDIA6 antibody is suitable to detect PDIA6 in samples from Human, Mouse and Rat. It has been validated for WB, FACS, IF, ELISA and IHC (p).

Quick Overview for PDIA6 antibody (AA 20-440) (ABIN7871874)

Target: PDIA6 (Protein Disulfide Isomerase Family A, Member 6 (PDIA6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDIA6 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PDIA6 Antibody

Binding Specificity: AA 20-440

Purpose: ERp5 Antibody / Endoplasmic reticulum protein 5 / PDIA6

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids L20-L440) was used as the immunogen for the ERp5 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ERp5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ERp5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PDIA6

Target: PDIA6 (Protein Disulfide Isomerase Family A, Member 6 (PDIA6))

Alternative Name: ERp5

Background: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. This protein inhibits the aggregation of misfolded proteins and exhibits both isomerase and chaperone activity. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: Q15084

Pathways: ER-Nucleus Signaling, Cell RedoxHomeostasis