GMP Synthase antibody (AA 20-670)

Catalog No. ABIN7871882

This Rabbit Polyclonal antibody specifically detects GMP Synthase in IHC (p). It exhibits reactivity toward Zebrafish (Danio rerio).

Quick Overview for GMP Synthase antibody (AA 20-670) (ABIN7871882)

Target: GMP Synthase (GMPS) (Guanine Monophosphate Synthetase (GMPS))

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GMP Synthase antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GMP Synthase Antibody

Binding Specificity: AA 20-670

Purpose: Zebrafish Gmps Antibody / GMP synthase

Purification: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish Gmps recombinant protein (amino acids L20-K670) was used as the immunogen for the Zebrafish Gmps antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal dilution of the Zebrafish Gmps antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Zebrafish Gmps antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for GMP Synthase

Target: GMP Synthase (GMPS) (Guanine Monophosphate Synthetase (GMPS))

Alternative Name: Gmps

Background: Guanosine monophosphate synthetase, also known as GMPS is an enzyme that converts xanthosine monophosphate to guanosine monophosphate. In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.

UniProt: B8JLW8

Pathways: Ribonucleoside Biosynthetic Process