HSP70 1A antibody (AA 200-400)

Catalog No. ABIN7872021

The Mouse Monoclonal anti-HSP70 1A antibody is suitable to detect HSP70 1A in samples from Human. It has been validated for IHC (p).

Quick Overview for HSP70 1A antibody (AA 200-400) (ABIN7872021)

Target: HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HSP70 1A antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: HSPA1A-7932

Product Details anti-HSP70 1A Antibody

Binding Specificity: AA 200-400

Purpose: HSP70-1A Antibody / Heat shock 70 kDa protein 1A

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 200-400) from the human protein was used as the immunogen for the HSP70-1A antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the HSP70-1A antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the HSP70-1A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for HSP70 1A

Target: HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

Alternative Name: HSP70-1A

Background: This intronless gene encodes a 70 kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1.The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq]

UniProt: P0DMV8

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process