The Mouse Monoclonal anti-IL18RAP antibody (Clone IL18RAP-7771) (ABIN7872022) specifically detects IL18RAP in IHC (p).
The antibody is reactive with Human samples.
Interleukin-18 receptor accessory protein Antibody / IL18RAP (azide and preservative free)
Purification
Protein A/G affinity
Immunogen
A recombinant partial protein sequence (within amino acids 200-400) from the human protein was used as the immunogen for the Interleukin-18 receptor accessory protein antibody.
Optimal dilution of the Interleukin-18 receptor accessory protein antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Preservative
Azide free
Storage
-20 °C
Storage Comment
Aliquot the Interleukin-18 receptor accessory protein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
IL18RAP
(Interleukin 18 Receptor Accessory Protein (IL18RAP))
Alternative Name
Interleukin-18 receptor accessory protein
Background
The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]