IL18RAP antibody (AA 200-400)

Catalog No. ABIN7872023

This Mouse Monoclonal antibody specifically detects IL18RAP in IHC (p). It exhibits reactivity toward Human.

Quick Overview for IL18RAP antibody (AA 200-400) (ABIN7872023)

Target: IL18RAP (Interleukin 18 Receptor Accessory Protein (IL18RAP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL18RAP antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: IL18RAP-7771

Product Details anti-IL18RAP Antibody

Binding Specificity: AA 200-400

Purpose: Interleukin-18 receptor accessory protein Antibody / IL18RAP

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 200-400) from the human protein was used as the immunogen for the Interleukin-18 receptor accessory protein antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the Interleukin-18 receptor accessory protein antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Interleukin-18 receptor accessory protein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for IL18RAP

Target: IL18RAP (Interleukin 18 Receptor Accessory Protein (IL18RAP))

Alternative Name: Interleukin-18 receptor accessory protein

Background: The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]

UniProt: O95256