Thrombospondin 1 antibody (AA 200-400)

Catalog No. ABIN7872060

The Mouse Monoclonal anti-Thrombospondin 1 antibody is suitable to detect Thrombospondin 1 in samples from Human. It has been validated for ELISA and IHC (p).

Quick Overview for Thrombospondin 1 antibody (AA 200-400) (ABIN7872060)

Target: Thrombospondin 1 (THBS1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Thrombospondin 1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: THBS1-4532

Product Details anti-Thrombospondin 1 Antibody

Binding Specificity: AA 200-400

Purpose: Thrombospondin-1 Antibody / THBS1 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 200-400) from the human protein was used as the immunogen for the Thrombospondin-1 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the Thrombospondin-1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the Thrombospondin-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Thrombospondin 1

Target: Thrombospondin 1 (THBS1)

Alternative Name: Thrombospondin-1

Background: The thrombospondin proteins (TSP 1-4) compose a family of glycoproteins that are involved in cell-to-cell and cell-to-matrix signaling. These extracellular, cell surface proteins form complexes of both homo- and heteromultimers. Thrombospondins play a role in development, aggregation of platelets, adhesion and migration of cells, and progression of cells through the growth cycle. Thrombospondin 1 is released from platelets in response to Thrombin stimulation and is a transient component of the extracellular matrix of developing and repairing tissues. Thrombospondin 2 shares a high degree of homology with Thrombospondin 1 and is thought to have overlapping but unique functions. Thrombospondin 3 is a developmentally regulated heparin binding protein. Thrombospondin 4 is neuronally expressed and stimulates neurite outgrowth.

UniProt: P07996

Pathways: Autophagy