SCYL2 antibody (AA 208-909)

Catalog No. ABIN7872112

The Rabbit Polyclonal anti-SCYL2 antibody (ABIN7872112) specifically detects SCYL2 in WB, ELISA, IF and FACS. The antibody is reactive with Human samples.

Quick Overview for SCYL2 antibody (AA 208-909) (ABIN7872112)

Target: SCYL2 (SCY1-Like 2 (SCYL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCYL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-SCYL2 Antibody

Binding Specificity: AA 208-909

Purpose: CVAK104 Antibody / SCYL2

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids E208-Q909) was used as the immunogen for the CVAK104 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the CVAK104 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the CVAK104 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SCYL2

Target: SCYL2 (SCY1-Like 2 (SCYL2))

Alternative Name: CVAK104

Background: SCY1-like protein 2, also called Coated vesicle-associated kinase of 104 kDa and CVAK104, is a protein that in humans is encoded by the SCYL2 gene. The protein encoded by this gene associates with clathrin-coated complexes at the plasma membrane and with endocytic coated vesicles. The encoded protein phosphorylates the beta2 subunit of the plasma membrane adapter complex AP2 and interacts with clathrin, showing involvement in clathrin-dependent pathways between the trans-Golgi network and the endosomal system. In addition, this protein has a role in the Wnt signaling pathway by targeting frizzled 5 (Fzd5) for lysosomal degradation. Two transcript variants encoding the same protein have been found for this gene.

UniProt: Q6P3W7