Apolipoprotein D antibody (AA 21-119)

Catalog No. ABIN7872127

The Mouse Monoclonal anti-Apolipoprotein D antibody (Clone APOD-3414) (ABIN7872127) specifically detects Apolipoprotein D in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Apolipoprotein D antibody (AA 21-119) (ABIN7872127)

Target: Apolipoprotein D (APOD)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Apolipoprotein D antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: APOD-3414

Product Details anti-Apolipoprotein D Antibody

Binding Specificity: AA 21-119

Purpose: APOD Antibody / Apolipoprotein D

Purification: Protein G affinity chromatography

Immunogen: A portion of amino acids 21-119 from the human protein was used as the immunogen for the APOD antibody.

Isotype: IgG2c, kappa

Application Details

Application Notes: Optimal dilution of the APOD antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the APOD antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Apolipoprotein D

Target: Apolipoprotein D (APOD)

Alternative Name: APOD

Background: Lipids, such as phospholipids, triacylglycerols and cholesterol, are weakly soluble in aqueous solution and therefore are transported by circulation as components of lipoproteins. Lipoproteins are globular particles that consist of a non-polar core of triacylglycerols and cholesteryl esters surrounded by phospholipid, cholesterol and an amphiphilic coating of protein, known as apolipoproteins (apo). These complexes allow the dissolution and shuttling of their non-polar lipid components. At least nine different apolipoproteins are distributed in significant amounts in different human lipoproteins. Apolipoprotein D (apoD) is a member of the lipocalin superfamily of transporter proteins that bind small hydrophobic molecules, including arachidonic acid (AA). The ability of apoD to bind AA implicates it in pathways associated with membrane phospholipid signal transduction and metabolism. apoD expression has been shown to correlate both with cell cycle arrest and with prognosis in several types of malignancy, including central nervous system astrocytomas and medulloblastomas.

UniProt: P05090

Pathways: Platelet-derived growth Factor Receptor Signaling