LRRC40 antibody (AA 21-598)

Catalog No. ABIN7872178

The Rabbit Polyclonal anti-LRRC40 antibody (ABIN7872178) specifically detects LRRC40 in ELISA and WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for LRRC40 antibody (AA 21-598) (ABIN7872178)

Target: LRRC40 (Leucine Rich Repeat Containing 40 (LRRC40))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC40 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-LRRC40 Antibody

Binding Specificity: AA 21-598

Purpose: LRRC40 Antibody / Leucine rich repeat containing 40

Purification: Immunogen affinity purified

Immunogen: E.coli-derived human LRRC40 recombinant protein (Position: R21-D598) was used as the immunogen for the LRRC40 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the LRRC40 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the LRRC40 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for LRRC40

Target: LRRC40 (Leucine Rich Repeat Containing 40 (LRRC40))

Alternative Name: LRRC40

Background: The LRRC40 antibody is designed to target leucine rich repeat containing 40, a protein that belongs to the large family of leucine rich repeat (LRR) domain containing proteins. Members of this family are defined by tandem repeats of a leucine rich motif that forms a structural scaffold for protein-protein interactions. LRRC40 is encoded by the LRRC40 gene in humans and is conserved across vertebrate species, suggesting it plays an essential biological role. Although the precise cellular function of LRRC40 remains under investigation, studies indicate it may be involved in processes such as intracellular signaling, assembly of multiprotein complexes, and regulation of protein localization. The broad distribution of leucine rich repeat proteins across diverse cell types makes LRRC40 a promising candidate for understanding protein interaction networks. Research into its potential involvement in human disease pathways continues to expand, highlighting the utility of the LRRC40 antibody for experimental investigations.

LRRC40 has been detected in a variety of tissues, including immune cells, brain, heart, and reproductive tissues. Leucine rich repeat proteins often mediate key developmental processes, including nervous system patterning and immune recognition, making antibodies against these proteins critical tools in functional studies. Recent data suggests LRRC40 may interact with cytoskeletal regulators or molecular motors, positioning it as a possible contributor to cell movement or organelle transport. This potential role has led to interest in using the LRRC40 antibody in immunohistochemistry, flow cytometry, and western blotting to evaluate protein expression in different tissues and disease contexts.

Beyond general protein interaction research, LRRC40 may be relevant in cancer biology. Several high-throughput expression datasets have reported altered LRRC40 mRNA or protein levels in certain malignancies, suggesting it could contribute to tumor progression or serve as a biomarker. Functional exploration using LRRC40 antibody reagents can help determine whether these correlations reflect causal roles or secondary effects. In neuroscience, the LRR protein family has established links to synapse formation and plasticity, raising the possibility that LRRC40 contributes to neural network development. The LRRC40 antibody can support this line of research by enabling the visualization and quantification of protein levels in neuronal systems.

As with other antibodies provided by NSJ Bioreagents, the LRRC40 antibody is suitable for research use only and is validated for multiple assay platforms. Western blotting enables the detection of protein size and abundance, while immunofluorescence and immunohistochemistry allow cellular and tissue localization studies. Flow cytometry may be employed to monitor LRRC40 expression in different immune subsets. By supplying consistent and specific recognition of this target, the antibody allows researchers to probe questions ranging from cell signaling to pathology. Future work may clarify whether LRRC40 plays a regulatory role in disease development, and the availability of the LRRC40 antibody provides an essential tool to accelerate this discovery.

UniProt: Q9H9A6