SOD3 antibody (AA 22-161)

Catalog No. ABIN7872278

This Rabbit Polyclonal antibody specifically detects SOD3 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SOD3 antibody (AA 22-161) (ABIN7872278)

Target: SOD3 (Superoxide Dismutase 3, Extracellular (SOD3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOD3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SOD3 Antibody

Binding Specificity: AA 22-161

Purpose: Superoxide Dismutase 3 Antibody / SOD3

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids E22-A161) was used as the immunogen for the Superoxide Dismutase 3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Superoxide Dismutase 3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Superoxide Dismutase 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SOD3

Target: SOD3 (Superoxide Dismutase 3, Extracellular (SOD3))

Alternative Name: Superoxide Dismutase 3

Background: SOD3 (SUPEROXIDE DISMUTASE 3), also called SUPEROXIDE DISMUTASE, EXTRACELLULAR, EC-SOD, and Cu-Zn, is an enzyme that in humans is encoded by the SOD3 gene. This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. Hendrickson et al. (1990) mapped the SOD3 gene to 4pter-q21 by a study of somatic cell hybrids. Stern et al. (2003) narrowed the assignment to 4p15.3-p15.1 by somatic cell and radiation hybrid analysis, linkage mapping, and FISH. The product of this gene is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM.

UniProt: P08294