SLAMF6 antibody (AA 22-332)

Catalog No. ABIN7872318

The Rabbit Polyclonal anti-SLAMF6 antibody is suitable to detect SLAMF6 in samples from Human. It has been validated for WB, ELISA and FACS.

Quick Overview for SLAMF6 antibody (AA 22-332) (ABIN7872318)

Target: SLAMF6 (SLAM Family Member 6 (SLAMF6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLAMF6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-SLAMF6 Antibody

Binding Specificity: AA 22-332

Purpose: SLAMF6 Antibody

Purification: Antigen affinity chromatography

Immunogen: An E.coli-derived human recombinant protein (amino acids Q22-V332) was used as the immunogen for the SLAMF6 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SLAMF6 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SLAMF6 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SLAMF6

Target: SLAMF6 (SLAM Family Member 6 (SLAMF6))

Alternative Name: SLAMF6

Background: SLAM family member 6 is a protein that in humans is encoded by the SLAMF6 gene. The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

UniProt: Q96DU3