USF2 antibody (AA 220-346)

Catalog No. ABIN7872345

The Mouse Monoclonal anti-USF2 antibody is suitable to detect USF2 in samples from Human. It has been validated for IF, IHC (p) and FACS.

Quick Overview for USF2 antibody (AA 220-346) (ABIN7872345)

Target: USF2 (Upstream Transcription Factor 2, C-Fos Interacting (USF2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This USF2 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: PCRP-USF2-1A7

Product Details anti-USF2 Antibody

Binding Specificity: AA 220-346

Purpose: Upstream stimulatory factor 2 Antibody / USF2

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 220-346) from the human protein was used as the immunogen for the Upstream stimulatory factor 2 antibody.

Isotype: IgG2c, kappa

Application Details

Application Notes: Optimal dilution of the Upstream stimulatory factor 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Upstream stimulatory factor 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for USF2

Target: USF2 (Upstream Transcription Factor 2, C-Fos Interacting (USF2))

Alternative Name: Upstream stimulatory factor 2

Background: The ubiquitously expressed cellular upstream stimulatory factor (USF) consists of USF-1 and USF-2 polypeptides which independently exhibit site-specific DNA binding and are members of the c-Myc-related family of regulatory factors containing helix-loop-helix domains. USF also contains a leucine repeat that is required for efficient DNA binding. USF was originally identified as an upstream stimulatory factor that binds the core sequence CACGTG in the adenovirus late promoter. These findings, together with the demonstration of cooperative interaction between USF and the initiatorbinding protein, TFII-I, raises the possibility of a more general involvement of USF in transcriptional regulation. While expression of both USF-1 and USF-2 species is ubiquitous, different ratios of USF homo- and heterodimers are found in different cell types.

UniProt: Q15853