MNT antibody (AA 222-582)

Catalog No. ABIN7872372

The Rabbit Polyclonal anti-MNT antibody is suitable to detect MNT in samples from Human. It has been validated for WB, ELISA and IF.

Quick Overview for MNT antibody (AA 222-582) (ABIN7872372)

Target: MNT (MNT, MAX Dimerization Protein (MNT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MNT antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-MNT Antibody

Binding Specificity: AA 222-582

Purpose: Max-binding protein MNT Antibody / MNT

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (R222-A582) was used as the immunogen for the Max-binding protein MNT antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Max-binding protein MNT antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Max-binding protein MNT antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for MNT

Target: MNT (MNT, MAX Dimerization Protein (MNT))

Alternative Name: Max-binding protein MNT

Background: MNT (Max-binding protein MNT) is a Max-binding protein that is encoded by the MNT gene The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.

UniProt: Q99583

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation