YTHDF3 antibody (AA 228-257)

Catalog No. ABIN7872420

The Rabbit Polyclonal anti-YTHDF3 antibody is suitable to detect YTHDF3 in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for YTHDF3 antibody (AA 228-257) (ABIN7872420)

Target: YTHDF3 (YTH Domain Family, Member 3 (YTHDF3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YTHDF3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-YTHDF3 Antibody

Binding Specificity: AA 228-257

Purpose: YTHDF3 Antibody / YTH domain-containing family protein 3

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 228-257 from the human protein was used as the immunogen for the YTHDF3 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the YTHDF3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the YTHDF3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for YTHDF3

Target: YTHDF3 (YTH Domain Family, Member 3 (YTHDF3))

Alternative Name: YTHDF3

Background: YTHDF3 belongs to a family of proteins with YTH domains, which are specialized RNA-binding domains that help to recognize and regulate RNA molecules. YTHDF3 specifically plays a key role in the regulation of mRNA degradation and translation, ultimately influencing gene expression. By binding to specific RNA molecules, YTHDF3 can either promote the degradation of the RNA or enhance its translation into proteins. Studies have shown that YTHDF3 can modulate the expression of genes involved in immune responses, development, and cancer progression and may play a role in stem cell differentiation and embryonic development.

UniProt: Q7Z739