Recombinant LMO2 antibody (AA 23-140)

Catalog No. ABIN7872476

This Mouse Monoclonal antibody specifically detects LMO2 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant LMO2 antibody (AA 23-140) (ABIN7872476)

Target: LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LMO2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RLMO2-1971

Product Details anti-LMO2 Antibody

Binding Specificity: AA 23-140

Purpose: Recombinant LMO2 Antibody / Rhombotin 2

Purification: Protein A/G affinity

Immunogen: A portion of amino acids 23-140 was used as the immunogen for the recombinant LMO2 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the recombinant LMO2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the recombinant LMO2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for LMO2

Target: LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Alternative Name: LMO2

Background: The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. It has a particular function in normal and lymphatic endothelial cells involving the regulation of angiogenesis and lymph-angiogenesis. Immunohistochemical studies have also demonstrated expression of LMO2 in both normal germinal center B-cells and germinal center-derived B-cell lymphomas, including follicular lymphoma and diffuse large B-cell lymphoma.The use of anti-LMO2 is valuable as a tool in the identification of lymphomas of B-cell origin.LMO2 is useful in differentiating follicular lymphoma (LMO2+) from nodal marginal zone lymphoma (LM02-). It also is positive in Hodgkin s and Burkitt s lymphomas.

UniProt: P25791

Pathways: Chromatin Binding