LMO2 antibody (AA 23-140)

Catalog No. ABIN7872479

This Mouse Monoclonal antibody specifically detects LMO2 in WB, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for LMO2 antibody (AA 23-140) (ABIN7872479)

Target: LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LMO2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: LMO2-1971

Product Details anti-LMO2 Antibody

Binding Specificity: AA 23-140

Purpose: LMO2 Antibody / Rhombotin 2 (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: A recombinant human partial protein (amino acids 23-140) was used as the immunogen for the LMO2 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the LMO2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the LMO2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for LMO2

Target: LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Alternative Name: LMO2

Background: The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. It has a particular function in normal and lymphatic endothelial cells involving the regulation of angiogenesis and lymph-angiogenesis. Immunohistochemical studies have also demonstrated expression of LMO2 in both normal germinal center B-cells and germinal center-derived B-cell lymphomas, including follicular lymphoma and diffuse large B-cell lymphoma.The use of anti-LMO2 is valuable as a tool in the identification of lymphomas of B-cell origin. LMO2 is useful in differentiating follicular lymphoma (LMO2+) from nodal marginal zone lymphoma (LM02-). It also is positive in Hodgkin s and Burkitt s lymphomas.

UniProt: P25791

Pathways: Chromatin Binding