ICOSLG antibody (AA 23-149)

Catalog No. ABIN7872488

This Mouse Monoclonal antibody specifically detects ICOSLG in IHC (p). It exhibits reactivity toward Human.

Quick Overview for ICOSLG antibody (AA 23-149) (ABIN7872488)

Target: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ICOSLG antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: ISLG-1

Product Details anti-ICOSLG Antibody

Binding Specificity: AA 23-149

Purpose: ICOS Ligand Antibody / ICOS-L / B7RP-1

Purification: Protein G affinity chromatography

Immunogen: A recombinant fragment of human ICOSLG / B7RP-1 protein within amino acids 23-149 was used as the immunogen for the ICOS Ligand antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the ICOS Ligand antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the ICOS Ligand antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for ICOSLG

Target: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Alternative Name: ICOS Ligand

Background: Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion, induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity). [UniProt]

UniProt: O75144

Pathways: Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation