SLC6A1 antibody (AA 23-215)

Catalog No. ABIN7872506

This Rabbit Polyclonal antibody specifically detects SLC6A1 in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for SLC6A1 antibody (AA 23-215) (ABIN7872506)

Target: SLC6A1 (GAT1) (GABA Transporter 1 (GAT1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC6A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SLC6A1 Antibody

Binding Specificity: AA 23-215

Purpose: GABA Transporter 1 Antibody / GAT-1 / SLC6A1

Purification: Antigen affinity chromatography

Immunogen: An E.coli-derived human recombinant protein (amino acids A23-A215) was used as the immunogen for the GABA Transporter 1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the GABA Transporter 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the GABA Transporter 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SLC6A1

Target: SLC6A1 (GAT1) (GABA Transporter 1 (GAT1))

Alternative Name: GABA Transporter 1

Background: GABA transporter 1 (GAT1), also known as sodium- and chloride-dependent GABA transporter 1, is a protein that in humans is encoded by the SLC6A1 gene. GABA Transporter 1 uses Na+ and Cl- to create a gradient, which removes or adds GABA to extracellular spaces in the cerebrum and cerebellum. The stoichiometry for GABA Transporter 1 is 2 Na+: 1 Cl-: 1 GABA. The activity of GAT1 is largely dependent on the presence of Na+, while Cl- assists by increasing the ability for GAT-1 to uptake GABA.

UniProt: P30531