EIF4G2 antibody (AA 23-889)

Catalog No. ABIN7872557

This Rabbit Polyclonal antibody specifically detects EIF4G2 in WB, ELISA, IF and FACS. It exhibits reactivity toward Human, Mouse, Rat and Monkey.

Quick Overview for EIF4G2 antibody (AA 23-889) (ABIN7872557)

Target: EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF4G2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-EIF4G2 Antibody

Binding Specificity: AA 23-889

Purpose: EIF4G2 Antibody / Eukaryotic translation initiation factor 4 gamma 2 / DAP5

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids R23-Q889) was used as the immunogen for the EIF4G2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the EIF4G2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the EIF4G2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for EIF4G2

Target: EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))

Alternative Name: EIF4G2

Background: Eukaryotic translation initiation factor 4 gamma 2 (also called p97, NAT1, and DAP-5) is a protein that in humans is encoded by the EIF4G2 gene. Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3, eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

UniProt: P78344