Gelsolin antibody (AA 230-259)

Catalog No. ABIN7872561

The Rabbit Polyclonal anti-Gelsolin antibody is suitable to detect Gelsolin in samples from Human, Mouse and Rat. It has been validated for WB, FACS and IHC (p).

Quick Overview for Gelsolin antibody (AA 230-259) (ABIN7872561)

Target: Gelsolin (GSN)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Gelsolin antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Gelsolin Antibody

Binding Specificity: AA 230-259

Purpose: GSN Antibody / Gelsolin

Purification: Purified

Immunogen: A portion of amino acids 230-259 from the human protein was used as the immunogen for the GSN antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the GSN antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the GSN antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Gelsolin

Target: Gelsolin (GSN)

Alternative Name: GSN

Background: GSN binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this protein are a cause of familial amyloidosis Finnish type (FAF).

UniProt: P06396

Pathways: Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy