PSMA antibody (AA 232-433)

Catalog No. ABIN7872586

The Mouse Monoclonal anti-PSMA antibody (Clone GCP2-1) (ABIN7872586) specifically detects PSMA in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for PSMA antibody (AA 232-433) (ABIN7872586)

Target: PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PSMA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: GCP2-1

Product Details anti-PSMA Antibody

Binding Specificity: AA 232-433

Purpose: FOLH1 Antibody / PSMA

Purification: Protein G affinity chromatography

Immunogen: A portion of amino acids 232-433 from the human protein was used as the immunogen for this FOLH1 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the FOLH1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the FOLH1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for PSMA

Target: PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

Alternative Name: FOLH1

Background: Folate hydrolase 1 (FOLH1), also known as Prostate-specific membrane antigen (PSMA), has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression. [UniProt]

UniProt: Q04609