Recombinant Inhibin alpha antibody (AA 233-362)

Catalog No. ABIN7872590

This Mouse Monoclonal antibody specifically detects Inhibin alpha in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant Inhibin alpha antibody (AA 233-362) (ABIN7872590)

Target: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Inhibin alpha antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: RINHA-6919

Product Details anti-Inhibin alpha Antibody

Binding Specificity: AA 233-362

Purpose: Recombinant INHA Antibody / Inhibin alpha (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A portion of amino acids 233-362 was used as the immunogen for the recombinant INHA antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the recombinant INHA antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the recombinant INHA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Inhibin alpha

Target: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Alternative Name: INHA

Background: It recognizes a 47 kDa protein, which is identified as alpha sub-unit of Inhibin. It is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises two subunits, Inhibin A and Inhibin B. Each subunit consists of the same ) superfamily. Antibodies against Inhibin are useful in making a differentiation between adrenal cortical tumors and renal cell carcinoma. Sex cord stromal tumors of the ovary as well as trophoblastic tumors also demonstrate cytoplasmic positivity. Inhibin antibody is also used to make the differential diagnosis of intra-uterine vs. ectopic pregnancy in endometrial curetting.

UniProt: P05111

Pathways: Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion