Recombinant Inhibin alpha antibody (AA 233-362)

Catalog No. ABIN7872591

The Mouse Monoclonal anti-Inhibin alpha antibody is suitable to detect Inhibin alpha in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for Recombinant Inhibin alpha antibody (AA 233-362) (ABIN7872591)

Target: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Inhibin alpha antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RINHA-6919

Product Details anti-Inhibin alpha Antibody

Binding Specificity: AA 233-362

Purpose: Recombinant INHA Antibody / Inhibin alpha

Purification: Protein A/G affinity

Immunogen: A portion of amino acids 233-362 was used as the immunogen for the recombinant INHA antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the recombinant INHA antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the recombinant INHA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Inhibin alpha

Target: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Alternative Name: INHA

Background: It recognizes a 47 kDa protein, which is identified as alpha sub-unit of Inhibin. It is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises two subunits, Inhibin A and Inhibin B. Each subunit consists of the same ) superfamily. Antibodies against Inhibin are useful in making a differentiation between adrenal cortical tumors and renal cell carcinoma. Sex cord stromal tumors of the ovary as well as trophoblastic tumors also demonstrate cytoplasmic positivity. Inhibin antibody is also used to make the differential diagnosis of intra-uterine vs. ectopic pregnancy in endometrial curetting.

UniProt: P05111

Pathways: Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion