Inhibin alpha antibody (AA 233-362)

Catalog No. ABIN7872594

The Mouse Monoclonal anti-Inhibin alpha antibody is suitable to detect Inhibin alpha in samples from Human. It has been validated for IHC (p).

Quick Overview for Inhibin alpha antibody (AA 233-362) (ABIN7872594)

Target: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Inhibin alpha antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: INHA-1168

Product Details anti-Inhibin alpha Antibody

Binding Specificity: AA 233-362

Purpose: INHA Antibody / Inhibin alpha (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: A portion of amino acids 233-362 from the human protein was used as the immunogen for the INHA antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the INHA antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the INHA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Inhibin alpha

Target: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Alternative Name: INHA

Background: It recognizes a 47 kDa protein, which is identified as alpha sub-unit of Inhibin. It is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises two subunits, Inhibin A and Inhibin B. Each subunit consists of the same ) superfamily. Antibodies against Inhibin are useful in making a differentiation between adrenal cortical tumors and renal cell carcinoma. Sex cord stromal tumors of the ovary as well as trophoblastic tumors also demonstrate cytoplasmic positivity. Inhibin antibody is also used to make the differential diagnosis of intra-uterine vs. ectopic pregnancy in endometrial curetting.

UniProt: P05111

Pathways: Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion