RED1 antibody (AA 234-714)

Catalog No. ABIN7872606

The Rabbit Polyclonal anti-RED1 antibody is suitable to detect RED1 in samples from Human, Rat and Mouse. It has been validated for WB, ELISA and FACS.

Quick Overview for RED1 antibody (AA 234-714) (ABIN7872606)

Target: RED1 (ADARB1) (Adenosine Deaminase, RNA-Specific, B1 (ADARB1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RED1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-RED1 Antibody

Binding Specificity: AA 234-714

Purpose: ADAR2 Antibody / ADARB1 / RED1

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids K234-R714) was used as the immunogen for the ADAR2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ADAR2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ADAR2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for RED1

Target: RED1 (ADARB1) (Adenosine Deaminase, RNA-Specific, B1 (ADARB1))

Alternative Name: ADAR2

Background: Double-stranded RNA-specific editase 1 is an enzyme that in humans is encoded by the ADARB1 gene. This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.

UniProt: P78563