FHL2 antibody (AA 235-279)

Catalog No. ABIN7872607

The Rabbit Polyclonal anti-FHL2 antibody (ABIN7872607) specifically detects FHL2 in IF and IHC (p). The antibody is reactive with Zebrafish (Danio rerio) samples.

Quick Overview for FHL2 antibody (AA 235-279) (ABIN7872607)

Target: FHL2 (Four and A Half LIM Domains 2 (FHL2))

Reactivity: Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FHL2 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FHL2 Antibody

Binding Specificity: AA 235-279

Purpose: Zebrafish Fhl2 Antibody / Fhl2a / Fhl2b

Purification: Antigen affinity chromatography

Immunogen: An E.coli-derived zebrafish Fhl2 recombinant protein (amino acids K235-I279) was used as the immunogen for the Zebrafish Fhl2 antibody. This antibody will detect the a and b isoforms.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal dilution of the Zebrafish Fhl2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Zebrafish Fhl2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for FHL2

Target: FHL2 (Four and A Half LIM Domains 2 (FHL2))

Alternative Name: Fhl2

Background: Four and a half LIM domains protein 2, also known as FHL-2, is a protein that in humans is encoded by the FHL2 gene. This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants encoding different isoforms have been identified.

UniProt: Q6AZB7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha