GALNS antibody (AA 236-263)

Catalog No. ABIN7872630

The Rabbit Polyclonal anti-GALNS antibody is suitable to detect GALNS in samples from Human. It has been validated for WB, IF, IHC (p) and FACS.

Quick Overview for GALNS antibody (AA 236-263) (ABIN7872630)

Target: GALNS (Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GALNS antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-GALNS Antibody

Binding Specificity: AA 236-263

Purpose: GALNS Antibody

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 236-263 from the human protein was used as the immunogen for the GALNS antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the GALNS antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the GALNS antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for GALNS

Target: GALNS (Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS))

Alternative Name: GALNS

Background: This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder. [provided by RefSeq].

UniProt: P34059

Pathways: Glycosaminoglycan Metabolic Process