RALBP1 antibody (AA 239-506)
Quick Overview for RALBP1 antibody (AA 239-506) (ABIN7872650)
Target
See all RALBP1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 239-506
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Purpose
- RLIP1 Antibody / RALBP1
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Purification
- Antigen affinity purified
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Immunogen
- Recombinant human protein (amino acids K239-Q506) was used as the immunogen for the RLIP1 antibody.
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Isotype
- IgG2b
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Application Notes
- Optimal dilution of the RLIP1 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Storage
- 4 °C,-20 °C
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Storage Comment
- After reconstitution, the RLIP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- RALBP1 (RalA Binding Protein 1 (RALBP1))
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Alternative Name
- RLIP1
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Background
- RalA-binding protein 1, also called Ral-interacting protein 1, is a protein that in humans is encoded by the RALBP1 gene. Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive to the active state through the action of RALGDS, which in turn is activated by RAS. RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL. RALBP1 is also the dominant transporter of lipid peroxidation-derived glutathione conjugates and participates in several mitotic events, including inactivation of endocytosis and separation and polar movement of centrioles and appropriate distribution of mitochondria to daughter cells following mitosis.
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UniProt
- Q15311
Target
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