Desmoglein 2 antibody (AA 24-1020)

Catalog No. ABIN7872661

The Rabbit Polyclonal anti-Desmoglein 2 antibody (ABIN7872661) specifically detects Desmoglein 2 in WB, ELISA, IF, FACS and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Desmoglein 2 antibody (AA 24-1020) (ABIN7872661)

Target: Desmoglein 2 (DSG2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Desmoglein 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Desmoglein 2 Antibody

Binding Specificity: AA 24-1020

Purpose: Desmoglein 2 Antibody / DSG2

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids L24-E1020) was used as the immunogen for the Desmoglein 2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Desmoglein 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Desmoglein 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Desmoglein 2

Target: Desmoglein 2 (DSG2)

Alternative Name: Desmoglein 2

Background: Desmoglein-2 is a protein that in humans is encoded by the DSG2 gene. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in DSG2 display a high degree of penetrance. Disease expression was of variable severity with LV involvement a prominent feature. The low prevalence of classical ECG changes highlights the need to expand current diagnostic criteria to take account of LV disease, childhood disease expression, and incomplete penetrance.

UniProt: Q14126

Pathways: Cell-Cell Junction Organization