DCT antibody (AA 24-519)

Catalog No. ABIN7872702

The Rabbit Polyclonal anti-DCT antibody is suitable to detect DCT in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and FACS.

Quick Overview for DCT antibody (AA 24-519) (ABIN7872702)

Target: DCT (Dopachrome Tautomerase (DCT))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCT antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-DCT Antibody

Binding Specificity: AA 24-519

Purpose: DCT Antibody / L-dopachrome tautomerase / TYRP2 / TRP2

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids Q24-A519) was used as the immunogen for the DCT antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the DCT antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the DCT antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for DCT

Target: DCT (Dopachrome Tautomerase (DCT))

Alternative Name: DCT

Background: Dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2), also known as DCT, is a human gene. The TYR-related proteins, TRP1 and TRP2, are also specifically expressed in melanocytes, and they likewise contribute to the synthesis of melanin within the melanosomes. The TRPs, including TYR, all share a similar transmembrane region, contain two metal-binding regions and a cysteinerich epidermal growth factor motif, and are localized in the melanosomal membrane. These proteins, however, have distinct catalytic activity, and they individually contribute to the biosynthesis of melanin biopolymers. The TRPs are believed to exist as a multi-enzyme complex, as these proteins form aggregates together, and the expression of TRP1 also helps stabilize TYR in melanocytes.

UniProt: P40126