SFTPD antibody (AA 241-336)

Catalog No. ABIN7872738

The Mouse Monoclonal anti-SFTPD antibody is suitable to detect SFTPD in samples from Human. It has been validated for IHC (p).

Quick Overview for SFTPD antibody (AA 241-336) (ABIN7872738)

Target: SFTPD (Surfactant Protein D (SFTPD))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SFTPD antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SFTPD-4363

Product Details anti-SFTPD Antibody

Binding Specificity: AA 241-336

Purpose: Surfactant protein D Antibody / SFTPD

Purification: Protein A/G affinity

Immunogen: A portion of amino acids 241-336 was used as the immunogen for the Surfactant protein D antibody.

Isotype: IgG2c, kappa

Application Details

Application Notes: Optimal dilution of the Surfactant protein D antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Surfactant protein D antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for SFTPD

Target: SFTPD (Surfactant Protein D (SFTPD))

Alternative Name: Surfactant protein D

Background: Pulmonary surfactant is primarily responsible for lowering the surface tension at the air-liquid interface in the alveoli, a process that is essential for normal respiration. Pulmonary surfactant is a mixture of phospholipids and proteins, including four distinct surfactant-associated proteins (SPs), SP-A, SP-B, SP-C, SP-D. SP-B and SP-C are predominantly hydrophobic proteins that associate with lipids to promote the absorption of surfactant phospholipids and to reduce the surface tension in the alveoli. SP-A and SP-D are large multimeric proteins belonging to the family of calcium-dependent lectins, designated Collectins, which contribute to the innate immune system. Both SP-A and SP-D have been shown to protect against microbial challenge through binding to the lipid components of the bacterial cell wall and facilitating the rapid removal of microbials.

UniProt: P35247