LI Cadherin antibody (AA 242-418)

Catalog No. ABIN7872748

The Mouse Monoclonal anti-LI Cadherin antibody (Clone CDH17-2618) (ABIN7872748) specifically detects LI Cadherin in WB, FACS and IHC (p). The antibody is reactive with Human samples.

Quick Overview for LI Cadherin antibody (AA 242-418) (ABIN7872748)

Target: LI Cadherin

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LI Cadherin antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: CDH17-2618

Product Details anti-LI Cadherin Antibody

Binding Specificity: AA 242-418

Purpose: Cadherin 17 Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: A recombinant human partial protein (amino acids 242-418) was used as the immunogen for the Cadherin 17 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the Cadherin 17 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the Cadherin 17 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for LI Cadherin

Target: LI Cadherin

Alternative Name: Cadherin 17

Background: It recognizes a glycosylated protein of 120 kDa, which is identified as Cadherin 17 (also known as LI Cadherin). The cadherins are a family of Calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.

UniProt: Q12864