LI Cadherin antibody (AA 242-418)

Catalog No. ABIN7872757

The Mouse Monoclonal anti-LI Cadherin antibody (Clone CDH17-2612) (ABIN7872757) specifically detects LI Cadherin in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for LI Cadherin antibody (AA 242-418) (ABIN7872757)

Target: LI Cadherin

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LI Cadherin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CDH17-2612

Product Details anti-LI Cadherin Antibody

Binding Specificity: AA 242-418

Purpose: Cadherin 17 Antibody / CDH17

Purification: Protein G affinity

Immunogen: A portion of amino acids 242-418 from human Cadherin 17 protein was used as the immunogen for the Cadherin 17 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the Cadherin 17 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Cadherin 17 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for LI Cadherin

Target: LI Cadherin

Alternative Name: Cadherin 17

Background: Cadherin 17 (also known as LI Cadherin) is part of a family of Calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.

UniProt: Q12864