TDP2 antibody (AA 246-272)

Catalog No. ABIN7872784

The Rabbit Polyclonal anti-TDP2 antibody (ABIN7872784) specifically detects TDP2 in WB, IF, FACS and IHC (p). The antibody is reactive with Human samples.

Quick Overview for TDP2 antibody (AA 246-272) (ABIN7872784)

Target: TDP2 (tyrosyl-DNA phosphodiesterase 2 (TDP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TDP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TDP2 Antibody

Binding Specificity: AA 246-272

Purpose: Tyrosyl-DNA phosphodiesterase 2 Antibody / TDP2 / ETS1 associated protein II

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 246-272 from the human protein was used as the immunogen for the Tyrosyl-DNA phosphodiesterase 2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Tyrosyl-DNA phosphodiesterase 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Tyrosyl-DNA phosphodiesterase 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for TDP2

Target: TDP2 (tyrosyl-DNA phosphodiesterase 2 (TDP2))

Alternative Name: Tyrosyl-DNA phosphodiesterase 2

Background: This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.

UniProt: O95551