NRF1 antibody (AA 246-503)

Catalog No. ABIN7872788

This Mouse Monoclonal antibody specifically detects NRF1 in WB, IF, IHC (p) and FACS. It exhibits reactivity toward Human.

Quick Overview for NRF1 antibody (AA 246-503) (ABIN7872788)

Target: NRF1 (Nuclear Respiratory Factor 1 (NRF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NRF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: 2G4

Product Details anti-NRF1 Antibody

Binding Specificity: AA 246-503

Purpose: NRF1 Antibody

Purification: Affinity purified

Immunogen: A human recombinant protein (amino acids D246-Q503) was used as the immunogen for the NRF1 antibody.

Isotype: IgG2a

Application Details

Application Notes: Optimal dilution of the NRF1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the NRF1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for NRF1

Target: NRF1 (Nuclear Respiratory Factor 1 (NRF1))

Alternative Name: NRF1

Background: Nuclear respiratory factor 1, is also known as NRF1. This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for nuclear factor (erythroid-derived 2)-like 1 which has an official symbol of NFE2L1.

UniProt: Q16656

Pathways: Regulation of Lipid Metabolism by PPARalpha