Recombinant ADRP antibody (AA 249-376)

Catalog No. ABIN7872816

The Mouse Monoclonal anti-ADRP antibody is suitable to detect ADRP in samples from Human. It has been validated for ELISA and IHC (p).

Quick Overview for Recombinant ADRP antibody (AA 249-376) (ABIN7872816)

Target: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ADRP antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: RADFP-1493

Product Details anti-ADRP Antibody

Binding Specificity: AA 249-376

Purpose: Recombinant Adipophilin Antibody / Perilin 2 / ADRP / PLIN2 (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: A human recombinant partial protein (amino acids 249-376) was used as the immunogen for this Adipophilin antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the recombinant Adipophilin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant Adipophilin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for ADRP

Target: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Alternative Name: Adipophilin

Background: Recognizes a protein of 48 kDa, which is identified as Adipophilin. It belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.

UniProt: Q99541

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism