Recombinant ADRP antibody (AA 249-376)

Catalog No. ABIN7872817

The Mouse Monoclonal anti-ADRP antibody (Clone rADFP-1493) (ABIN7872817) specifically detects ADRP in ELISA and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant ADRP antibody (AA 249-376) (ABIN7872817)

Target: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ADRP antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RADFP-1493

Product Details anti-ADRP Antibody

Binding Specificity: AA 249-376

Purpose: Recombinant Adipophilin Antibody / Perilin 2 / ADRP / PLIN2

Purification: Protein G affinity chromatography

Immunogen: A human recombinant partial protein (amino acids 249-376) was used as the immunogen for this Adipophilin antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the recombinant Adipophilin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant Adipophilin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for ADRP

Target: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Alternative Name: Adipophilin

Background: Recognizes a protein of 48 kDa, which is identified as Adipophilin. It belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.

UniProt: Q99541

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism