Recombinant ADRP antibody (AA 249-376)

Catalog No. ABIN7872820

The Mouse Monoclonal anti-ADRP antibody (Clone rADFP-9321) (ABIN7872820) specifically detects ADRP in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant ADRP antibody (AA 249-376) (ABIN7872820)

Target: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ADRP antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: RADFP-9321

Product Details anti-ADRP Antibody

Binding Specificity: AA 249-376

Purpose: Adipose differentiation-related protein Antibody / ADRP / Adipophilin / Perilipin 2 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A recombinant fragment (within amino acids 249-376) of human Adipophilin protein was used as the immunogen for the Adipose differentiation-related protein antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the Adipose differentiation-related protein antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the Adipose differentiation-related protein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for ADRP

Target: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Alternative Name: Adipose differentiation-related protein

Background: Recognizes a protein of 48 kDa, which is identified as Adipophilin. It belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.

UniProt: Q99541

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism