NME7 antibody (AA 25-55)

Catalog No. ABIN7872884

This Rabbit Polyclonal antibody specifically detects NME7 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for NME7 antibody (AA 25-55) (ABIN7872884)

Target: NME7 (Nucleoside Diphosphate Kinase (NME7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NME7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-NME7 Antibody

Binding Specificity: AA 25-55

Purpose: NME7 Antibody / Nucleoside diphosphate kinase 7

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 25-55 from the human protein was used as the immunogen for the NME7 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the NME7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the NME7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for NME7

Target: NME7 (Nucleoside Diphosphate Kinase (NME7))

Alternative Name: NME7

Background: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

UniProt: Q9Y5B8