GDF9 antibody (AA 250-450)

Catalog No. ABIN7872906

The Mouse Monoclonal anti-GDF9 antibody is suitable to detect GDF9 in samples from Human. It has been validated for IHC (p).

Quick Overview for GDF9 antibody (AA 250-450) (ABIN7872906)

Target: GDF9 (Growth Differentiation Factor 9 (GDF9))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GDF9 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: GDF9-6458

Product Details anti-GDF9 Antibody

Binding Specificity: AA 250-450

Purpose: Growth Differentiation Factor 9 Antibody / GDF9

Purification: Protein A/G affinity

Immunogen: A recombinant fragment (within amino acids 250-450) of human Growth Differentiation Factor 9 protein was used as the immunogen for the Growth Differentiation Factor 9 antibody.

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal dilution of the Growth Differentiation Factor 9 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Growth Differentiation Factor 9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for GDF9

Target: GDF9 (Growth Differentiation Factor 9 (GDF9))

Alternative Name: Growth Differentiation Factor 9

Background: GDF9 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. GDF9 is expressed in oocytes and is thought to be required for ovarian folliculogenesis. GDF9/6458 can be used in assays to detect oocyte expression and has been shown to neutralize GDF9 biological activity.

UniProt: O60383