Recombinant TUBB3 antibody (AA 250-450)

Catalog No. ABIN7872926

This Mouse Monoclonal antibody specifically detects TUBB3 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant TUBB3 antibody (AA 250-450) (ABIN7872926)

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TUBB3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RTUBB3-7405

Product Details anti-TUBB3 Antibody

Binding Specificity: AA 250-450

Purpose: Recombinant TUBB3 Antibody / Beta Tubulin

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 250-450) from the human protein was used as the immunogen for the recombinant TUBB3 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the recombinant TUBB3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the recombinant TUBB3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for TUBB3

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Alternative Name: TUBB3

Background: This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. In adults, tubulin beta 3 (TUBB3) is primarily expressed in neurons and is commonly used as a neuronal marker. It plays an important role in neuronal cell proliferation and differentiation.

UniProt: Q13509

Pathways: Microtubule Dynamics, M Phase